Pharmacologic Management of Constipation
Commonly used ...

Pharmacologic Management of Constipation
Commonly used laxatives:
 • Bulk-forming laxatives - Psyllium, methylcellulose, polycarbophil
 • Osmotic laxatives - Sodium phosphate, polyethylene glycol, sorbitol, lactulose, magnesium hydroxide, magnesium citrate, magnesium sulfate
 • Stimulants - Diphenylmethane derivatives (bisacodyl, sodium picosulfate), anthraquinones (sennoside, aloe, cascara)
 • Stool softeners - Docusate sodium, docusate calcium
 • Lubricants - Mineral oil
Newer agents:
 • Chloride channel activators - Lubiprostone
 • Guanylate cyclase C receptor agonists - Linaclotide, plecanatide
 • Selective serotonin 5-HT4 receptor agonists - Prucalopride, cisapride, tegaserod
 • Ileal bile acid transporters inhibitors - Elobixibat

#Constipation #Management #treatment #medications #pharmacology
Contributed by

Dr. Gerald Diaz
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: | Twitter:

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