Lynch Syndrome:
 • "CRC + Endometrial/Ovarian + Stomach ...
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Description

Lynch Syndrome:
 • "CRC + Endometrial/Ovarian + Stomach + Urinary → Lynch Syndrome"
 • Autosomal Dominant, 1 in 279 people
 • Loss of expression in MLHI, MSH2, MSH6 or PMS2 or EPCAM genes
    → Mismatch Repair Defect → Microsatellite Instability (MSI)
 • Previously thought to be but can have polyps; Proximal > Distal

by Dean Ehrlich MD @DeanEhrlich_MD

#Lynch #Syndrome #diagnosis #management #gastroenterology
Contributed by

Dean Ehrlich
@DeanEhrlich_MD
Chief Fellow #UCLAGI @uclabiodesign Fellow, Former Chief Res @uclaimchiefs https://twitter.com/DeanEhrlich_MD #Endoscopy, #Innovation, #MedTech, #MedEd 
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