Vesiculobullous Rashes - THE ALGORITHMIC APPROACH 
Vesiculobullous ...
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Vesiculobullous Rashes - THE ALGORITHMIC APPROACH 
Vesiculobullous rashes provoke significant angst

in many physicians (Figure 5, page 14). However,

the differential diagnosis can be greatly simplified

by categorizing patients with these rashes as febrile

or afebrile and noting whether the rash distribution

is diffuse or localized. Patients with a diffuse

vesiculobullous rash and a fever may have varicella

or a more devastating illness, such as smallpox, disseminated

gonococcal disease, purpura fulminans, or

DIC. Necrotizing fasciitis and hand-foot-and-mouth

disease present with localized lesions and fever. In

afebrile patients with a diffuse vesiculobullous rash,

the differential diagnosis includes bullous pemphigus

(BP) and pemphigus vulgaris. These entities are

regularly confused, and it is essential to differentiate

urgently. However, the differential diagnosis is simpler

and less emergent in a patient who is afebrile

with a localized vesiculobullous rash; contact dermatitis,

herpes zoster, dyshidrotic eczema, and burns

(chemical or thermal) are included.


#Diagnosis #Dermatology #Vesicular #Vesiculobullous #Rash #Algorithm #Differential
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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