Pathology - Castleman disease. 

Mediastinal mass ...
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Pathology - Castleman disease. 


Mediastinal mass in a younger woman.

Histologic Features of Castleman disease, hyaline vascular type 

 - Increase in paracortical blood vessels 
 - Germinal center 'twinning' = rnost specific feature 
 - Hyalinized germinal centers with penetrati ngvessels 
 - Suggestion of mantle zone 'onion skinning' 

 - Michael Cascio, M.D.

@mjcascio


#Castleman #disease #Pathology #Smear #Microscopy #Clinical
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