Clinical manifestations of acute liver failure 


Brain: 

Hepatic encephalopathy,  

Cerebral edema,  

Intracranial hypertension,  

Seizures 


Kidney and adrenals: 

Hepatorenal syndrome,  

Hepatoadrenal syndrome,  

Electrolyte abnormalities


Liver: 

Loss of metabolic function,  

Hypoglycemia,  

Hyperammonemia,  

Coagulopathy,  

Lactic acidosis  


Systemic: 

Systemic inflammatory response,  

Immunosuppression,  

High energy expenditure  


Heart: 

High output state,  

Subclinical myocardial injury,  

Hepatocardiac syndrome 


Pancreas: 

pancreatitis 


Lungs: 

Acute lung injury,  

Acute respiratory distress syndrome,  

Hepatopulmonary syndrome  


Bone marrow: 

Frequent suppression,  

Anemia,  

Thrombocytopenia 


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