Summary of the adverse effects associated with the use of trimethoprim–sulfamethoxazole


Mnemonic - NOT RISKY?


N - Neurologic effects


O - Decreased oxygen- Rare

carrying capacity and

other hematologic

abnormalities


T - Toxic epidermal

necrolysis and other

hypersensitivity

reactions

R - Reproductive toxicity


I - Interactions with other

drugs


S - Sugar


K - Hyperkalemia and

other kidney effects


Y? - Why not consider an alternate antimicrobial?


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