Guide to Acute Kidney Injury (AKI)



What to ask/look for: 

 - HPI, PMH, full ROS 

 - Nephrotoxins (NSAlDs, contrast, OTCs, herbals, abx, illicits, chemo, immunosuppression) 

 - Hx of AKI/CKD 

 - Recent hypo/hypertension? 

 - TTE/liver fxn? 

 - BMP, cap, CBC w/ diff 

 - Urinalysis/microscopy/UOP/weights 

 - Urine Na/K/Cl/urea/protein/Cr 

 - Renal/bladder US w/ PVR 

 - CPK, uric acid (rhabdo/TLS) 



Causes of Inpatient AKI (Liano 1996) 

 - ATN - 45%

 - Pre-renal disease — 21% 

 - AKI on CKD— 13% (mostly ATN and pre-renal) 

 - Urinary tract obstruction — 10% (most often prostate related) 

 - Glomerulonephritis or vasculitis — 4% 

 - Atheroemboli — 1% 



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