Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP (Hemolysis, Elevated Liver tests, Low Platelets)
* Variant of pre-eclampsia
* High LDH, schistocytes, DIC
* Responds to delivery of child
* Severe cases may require plasma exchange
2) Fatty liver of pregnancy
* Severe coagulation defects and liver failure
* Responds to delivery of child
3) TTP
* Occurs most often in 2nd trimester
* Can support mother through pregnancy with plasma exchange
- Dr. Tom DeLoughery @Bloodman
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