JAK Inhibitors in 2019

Role in the therapeutic strategy ...
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Description

JAK Inhibitors in 2019



Role in the therapeutic strategy in 2019

 • RA: 2nd line after failure of conventional DMARDs 

 • PsoArth: after failure of NSAID, cDMARDs and/or biologics

 • Ulcerative colitis: 3rd line after failure of 5-ASA, GCs, cDMARDS and anti-TNF-apha



Efficacy (Rheumatoid Arthritis, Psoriatic Arthritis)

 • Superior to methotrexate

 • Noninferior to combination of methotrexate + anti-TNFapha

 • Efficacy as early as 3 weeks

 • Maximum efficacy at 3 mo.



By Romain Muller via Dr. Benjamin Terrier @TerrierBen



#JAKInhibitors #Indications #Rheumatology #Management
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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