UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020



Clinical Presentation

• Fever: hospitalized pts but only 50% on admit

• Myalgias 10-50%

• Respiratory: Cough 45-80%, dyspnea 20-50%

• URI sx (HA, sore throat, rhinorrhea) <20%

• GI: N/V, diarrhea <30%; can be only symptom 3-12%

• Cardiac: multiple case reports of myocarditis

• ENT: Taste or smell disorder in 34-89%, can occur before other symptoms appear

• Eye: conjunctivitis in 32% (single study)

Labs and Biomarkers

• WBC usually normal or low (leukopenia 17-45%, leukocytosis lymphopenia in 33-85%

• Platelets usually normal, can be low in <35%

• AST/ALT incr in 4-35%

• CRP incr in 61-86%, LDH incr in 27-75%

• PCT: >0.5 in 5-10% (higher % if severe or ICU)

• Troponin incr in 7-28% -> Incr risk complications, death

• Higher inflammatory markers (CRP, D-dimer, IL-6, TNF-a) associated w severe disease, death



- Dr. Jen Babik, UCSF COVID-19 ID Clinical Working Group 



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