Risk factors for hydroxychloroquine retinopathy
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Description

Risk factors for hydroxychloroquine retinopathy

 - Daily dosage > 5.0 mg/kg ABW - Largest study suggests that ABW-based dosing offers improved prediction of retinopathy risk

 - Daily dosage >6.5 mg/kg IBW - Might additionally predict retinopathy, particularly in obese patients, although this association is controversial

 - Prolonged hydroxychloroquine - Minimal risk with <5 years use; risk continues to rise over 10—25 years of use

 - High cumulative dose - Some studies suggest increased risk with > 600-1000g exposure

 - CKD - Increased risk associated with stage 3, 4, or 5 CKD in largest recent study

 - Tamoxifen use - Increased risk associated with concomitant tamoxifen use for months in largest recent study



#hydroxychloroquine #retinopathy #RiskFactors #ophthalmology 
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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