Hyperphosphatemia - Diagnosis and Management Summary
Signs/symptoms: ...
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Description

Hyperphosphatemia - Diagnosis and Management Summary

Signs/symptoms: acute hyperphosphatemia signs/symptoms result from effects of hypocalcemia (muscle cramps, tetany, tingling, perioral numbness), acute phosphate nephropathy (bowel prep); rarely sx from chronic hyperphosphatemia

Etiologies:

 • Acute phos load (TLS, rhabdo, exogenous/phosphate-containing laxatives); acute extracellular shift (DKA, lactic acidosis, severe hyperglycemia); acute or chronic kidney disease

 • Increased tubular reabsorption (vit D tox, hypoPTH)

 • Pseudohyperphos (hyperglobulinemia, hyperlipidemia, hyperbili, hemolysis)

Treatment: acute – normal saline (though can worsen hypoCa), dialysis; chronic – see Chronic Kidney Disease



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