Parenteral Anticoagulation
Heparin (UFH)
 - Binds ...
221
Description

Parenteral Anticoagulation

Heparin (UFH)

 - Binds & activates ATIII→ inactivates Xa & IIa

 - t1/2 60-90min

Enoxaparin (LMWH, Lovenox)

 - Binds & activates ATIII→ inactivates Xa >> IIa

 - t1/2 4.5-7hrs

Fondaparinux (Arixtra)

 - Binds & activates ATIII→ inactivates Xa only

 - t1/2 15-17hrs

Argatroban

 - Direct IIa (thrombin) inhibitor

 - t1/2 45min



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MGH White Book Manual
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Account created for the MGH Internal Medicine Housestaff Manual "White Book" - https://stk10.github.io/MGH-Docs/WhiteBook-2019-2020.pdf
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