TRANSFUSION MEDICINE TERMINOLOGY
ABO typing: front ...
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TRANSFUSION MEDICINE TERMINOLOGY

ABO typing: front type: A/B antigens (pt's RBC + reagent anti-A or B); back: anti-A or B in plasma (pt’s plasma + reagent RBCs)

Rh(D) typing: tests for D antigen on RBC (pt’s RBC + reagent anti-D) – NB: anti-D is not a naturally occurring antibody

Screening (T&S): tests for unexpected antibodies in pt’s plasma (pt’s plasma + screening RBC + Coomb’s reagent), “active” x3d

Crossmatching (T&C): final confirmation test by mixing pt’s plasma & donor RBC; performed just prior to transfusion

Therapeutic apheresis: extracorporeal treatment that selectively removes cells or other abnormal substances

 • Plasmapheresis: removes plasma. Indications: TTP, hyperviscosity sx, cryo, Guillain-Barre, CIDP, MG, ANCA, anti-GBM.

 • Plasma exchange: similar but w/ replacement (donor plasma). Indications: TTP (replace ADAMTS13)

 • Cytapheresis: removes abnl or excessive # blood cells; indications: hyperleukocytosis, thrombocytosis (goal WBC <100 and plts <1000), sickle cell crisis, severe babesiosis (high grade parasitemia >10, severe hemolysis, or pulm/liver/renal dz)

 • Direct antiglobulin test (DAT/Coomb’s Test): tests for Ab or complement on RBCs (RBCs + Coomb’s reagents [anti-IgG, anti-C3])



#transfusion #glossary #terminology #medicine #definitions
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