Retinoblastoma - MRI
 • Most common intra-ocular neoplasm ...
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Description

Retinoblastoma - MRI

 • Most common intra-ocular neoplasm in children.

 • Clinical Presentation: leukocoria (loss of red light reflex).

 • Epidemiology: most cases are diagnosed within the first 4 years of life.

 • Bilateral tumours (30-40%) almost always have a germline mutation.

 • Unilateral tumours (60-70%) are caused by a germline mutation in 15% of cases.

 • With germline mutations there is a risk of developing trilateral retinoblastoma, involving both globes and the pineal gland (pineoblastoma).

 • Metastases:

    - Direct spread into the orbit;

    - Leptomeningeal disease;

    - Haematogeneous metastases to bone, bone marrow and liver;

    - Rarely involvement of regional lymph nodes.



- Dr. Amar Chotai @DrAmarChotai



#Retinoblastoma #MRI #diagnosis #neuroradiology #pediatrics #radiology
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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