Autoimmune Rheumatologic Medications:
Drug/Class, ...
265
Description

Autoimmune Rheumatologic Medications:

Drug/Class, Indications and Common Toxicities

 • Azathioprine (AZA; Imuran) - DM/PM, RA, SLE nephritis, vasculitis

 • Cyclophosphamide (CYC; Cytoxan) - SLE (LN), vasculitis (most severe)

 • Hydroxychloroquine (HCQ; Plaquenil) - RA, SLE, Sjogren’s

 • Leflunomide (LFM; Arava) - PsA, RA

 • Methotrexate (MTX; Rheumatrex, Trexall, Otrexup, Rasuvo) - RA (first line), PsA

 • Mycophenolate Mofetil (MMF; CellCept) - AAV, DM/PM, PsA, Scleroderma, SLE

 • Sulfasalazine (5-ASA; Azulfidine) - AS, IBD, JRA, psoriasis, RA

 • Apremilast (Otezla); PDE4 inhibitor - PsA, severe psoriasis 

 • Tofacitinib (Xeljanz); JAK inhibitor - RA, AS, psoriasis

BIOLOGIC, non-TNF

 • Abatacept (Orencia); CTLA-4 - PsA, RA

 • Anakinra (Kineret); anti-IL-1R - AOSD/MAS, gout, Schnitzler syndrome

 • Belimumab (Benlysta); anti-BAFF - SLE

 • Canakinumab (Ilaris); anti-IL-1b - CAPS, CAD

 • Rituximab (Rituxan); anti-CD20 - APLAS, GPA/MPA, IgG4-RD, Scl-ILD, (SLE)

 • Tocilizumab (Actemra); anti-IL-6R - GCA, RA

 • Secukinumab (Cosentyx); anti-IL17A - AS, PsA, psoriasis

 • Ustekinumab (Stelara); anti-IL-12/23 - PsA, psoriasis 

 • IVIG - APLAS, DM/PM, IBM, IMNM, Kawasaki’s

BIOLOGIC, TNF inhibition

 • Adalimumab (Humira); anti-TNF - AS, IBD, PsA, psoriasis, RA

 • Infliximab (Remicade); anti-TNF - AS, IBD, PsA, psoriasis, RA

 • Golimumab (Simponi); anti-TNF - AS, IBD, PsA, RA

 • Certolizumab (Cimzia); anti-TNF - AS (axial), IBD, RA

 • Etanercept (Enbrel); sol. TNF-R - AS, PsA, psoriasis, RA



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