Results for: "pathophysiology"
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How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:<BR>
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext
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#Pathophysiology #Mechanism #Nephrology Mechanism and Appearance of Hill-Sachs and Bankart Lesions
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#Pathophysiology #Radiology #Mechanism #Bankart #HillSachs #Lesions Hormonal Regulation at Various Parts of the Menstrual Cycle<BR>
#Pathophysiology #Endocrinology #Hormones #Menstrual #Cycle #Regulation #Hormonal SEX HORMONE SYNTHESIS, REGULATION, AND FUNCTION - Steroidogenesis
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#Pathophysiology #Steroidogenesis #Androgens #Glucocorticoids #Mineralocorticoid Pathophysiology of Menopausal Transition
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#Pathophysiology #Endocrinology #Menopause #Menopausal #Transition Pathophysiology of Polycystic Ovarian Syndrome (PCOS)<BR>
#Pathophysiology #PCOS #Polycystic #Ovarian #Syndrome #Symptoms  Bone resorption and the relationship between osteoblasts and osteoclasts.  <BR>
RANK is expressed on the Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. 
<BR>Vitamin D Cardiac Myocyte Contractile cycle
<BR> - Ca2+ binds to TnC → TnI is inhibited → conformational change Risk factors for atherosclerosis<BR>
<BR>Modifiable risk factors:
<BR> - Dyslipidemia (elevated LDL, decreased HDL)
<BR> - Tobacco smoking
<BR> - Atherosclerosis - Stages of plaque development
<BR> 1. Fatty streak
<BR> 2. Plaque progression
<BR> 3. Plaque disruption
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#Pathophysiology #Cardiology Pathophysiology - Pathogenesis of Chronic Kidney Disease
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#Pathophysiology #Nephrology #Chronic #Kidney #Disease #CKD Diabetes – diabetic nephropathy
<BR>Majority of the literature in the area is applied to the diabetic nephropathy Complications of CKD
<BR> - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic; Regulation of GFR<BR>
Physiologically, GFR is auto-regulated very precisely with changes in the mean arterial pressure (MAP) Hormones Acting on the Nephron - Diuretics and Their Site of Action
<BR> 1) Acetazolamide
<BR> 2) Osmotic Renin-Angiotensin-Aldosterone System (RAAS) 
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#Pathophysiology #RAAS #Renin #Angiotensin #Aldosterone #System The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism<BR>
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism. Alcoholic ketoacidosis - Pathophysiology
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#Pathophysiology #Metabolism #Alcoholic #Ketoacidosis #Ketogenesis The biotrauma hypothesis of ventilator-induced lung injury. IL = interleukin; PEEP = positive end-expiratory pressure; Pplat Action potential in cardiomyocytes<BR>
The action potential in typical cardiomyocytes is composed of 5 phases (0-4), beginning Fungal Cell Walls and Antifungals sites of action:<BR>
#Pharmacology #Pathophysiology #Mechanism #Antifungals #CellWall #Location #Sites #Action Non-Traumatic Monocular Vision Loss - Open and Closed Angle Glaucoma Anatomy <BR>
#Diagnosis #Pathophysiology #Ophthalmology #Open #Closed Non-Traumatic Monocular Vision Loss - Open and Closed Angle Glaucoma Anatomy
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#Anatomy #Pathophysiology #Ophthalmology #Open #Closed #Angle Wernicke Encephalopathy Pathophysiology
Thiamine is a cofactor for the enzyme pyruvate dehydrogenase
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#Pathophysiology #Thiamine #Cofactor #Pyruvate #Dehydrogenase #Wernickes Vitamin deficiency causes clinical disease<BR>
Vitamin C deficiency causes scurvy.  Vitamin C is important for the Salicylate metabolism.<BR>
#Pathophysiology #Metabolism #Toxicology #Salicylate #Aspirin Salicylate Effect on Oxidative Phosphorylation (www.derangedphysiology.com)<BR>
#Pathophysiology #Toxicology #Toxicity #Salicylate #Aspirin #Oxidative #Phosphorylation How does IAH/ACS result in systemic end organ dysfunction? Through direct transmission of intra-abdominal pressure
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#Pathophysiology #ACS