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Generic Opana ER 40 mg contains oxymorphone in an extended-release formulation. The 40 mg strength refers to the amount of oxymorphone in the medication. Its extended-release design allows the active ingredient to be released gradually over time. Oxymorphone works primarily through opioid receptors in the central nervous system and can alter how the body perceives pain. Possible effects include drowsiness, dizziness, nausea, constipation, and reduced alertness. Like other opioids, oxymorphone can slow breathing, with greater risks when combined with alcohol, sedatives, or other substances that depress the nervous system. Extended-release tablets require careful handling and should not be crushed or altered unless specifically directed by a qualified healthcare professional.

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