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Generic Opana ER 40 mg contains 40 mg of oxymorphone in an extended-release formulation. Oxymorphone belongs to the opioid class and acts on receptors within the nervous system that influence pain perception. The ER formulation is designed to release the medicine over an extended period. Potential side effects include drowsiness, dizziness, nausea, vomiting, constipation, and reduced alertness. Opioids can also cause respiratory depression, which may become especially dangerous when combined with alcohol or other substances that slow nervous-system activity. Safe handling is important with this medication. It should be kept securely stored and away from children or anyone for whom it was not intended. Any severe breathing difficulty or extreme sedation requires immediate medical attention.

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