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Opana ER 40 mg: Formulation, Oxymorphone, and Responsible Use
Exploring Opana ER 40 mg

Opana ER 40 mg was an extended-release formulation of oxymorphone hydrochloride. It was classified as a prescription opioid analgesic and was historically used in the management of pain requiring continuous, around-the-clock opioid treatment.

The 40 mg strength represented the amount of oxymorphone hydrochloride contained in the tablet according to historical product labeling.

Why Extended Release Was Important

The design of Opana ER was centered on extended release. This formulation was intended to provide prolonged exposure to the medication compared with an immediate-release product.

However, the same formulation characteristic also meant that the tablets required careful handling. Historical labeling instructed patients not to break, chew, dissolve, or crush Opana ER tablets because altering the formulation could cause rapid release and absorption of oxymorphone.

Understanding the Opioid Class

Oxymorphone belongs to the opioid family. Opioids can provide significant analgesic effects, but they also affect several body systems.

Potential serious risks include respiratory depression, overdose, dependence, addiction, and misuse. These risks are especially important with long-acting opioid formulations.

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