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Methadone is a long-acting synthetic opioid that affects the body's opioid receptors. It has an important place in healthcare, including certain pain-management situations and treatment programs for opioid use disorder. Its long-lasting activity can help stabilize opioid withdrawal symptoms and cravings when used under appropriate clinical supervision. Methadone can also produce opioid-related effects such as drowsiness, constipation, nausea, and slowed breathing. The medication has important interactions with other drugs and substances, and some people may experience changes in heart rhythm. Because of its long duration and potential for serious adverse effects, methadone should be used carefully and monitored by qualified healthcare professionals.


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