Cawethejo preoperative HER2-directed therapy Tuaklahang

The trial included patients with HER2-positive early breast cancer who had received neoadjuvant treatment, which included a taxane-based chemotherapy and/or trastuzumab, and had residual invasive cancer in the breast or resected axillary nodes. Patients were randomly assigned to receive either T-DM1 (n = 743) or trastuzumab (n = 743). Patients were stratified by clinical stage, hormone-receptor status, preoperative HER2-directed therapy, and pathological nodal status after neoadjuvant therapy.

T-DM1 significantly reduced the risk for death compared with trastuzumab (unstratified HR = 0.66; 95% CI, 0.51-0.87; P = .003). Seven-year overall survival for the T-DM1 and trastuzumab groups were 89.1% and 84.4%, respectively (difference, 4.7 percentage points). As of the trial’s cutoff date of October 5, 2023, 70.1% of patients assigned T-DM1 and 62.0% of patients assigned trastuzumab were alive and still in the trial.

Deaths occurred in 89 patients (12.0%) in the T-DM1 group and 126 patients (17.0%) in the trastuzumab group. Of these deaths, 70 (79%) and 108 (86%) patients, respectively, died from breast cancer.

https://www.ticketmelon.com/phim/lat-mat-8-vong-tay-nang-full-lau-vietsub
https://www.ticketmelon.com/phim/tham-tu-kien-ky-an-khong-dau-full-lau-vietsub
https://www.ticketmelon.com/phim/thunderbolts-biet-doi-sam-set-full-lau-vietsub
https://www.ticketmelon.com/phim/mat-vu-phu-ho-full-lau-vietsub
https://www.ticketmelon.com/phim/tim-xac-ma-khong-dau-full-lau-vietsub
https://www.ticketmelon.com/phim/cuoi-ma-giai-han-full-lau-vietsub
https://www.ticketmelon.com/phim/mat-danh-ke-toan-2-full-lau-vietsub
https://www.ticketmelon.com/phim/lat-mat-7-mot-dieu-uoc-full-hd-vietsub-mien-phi
https://www.ticketmelon.com/phim/lat-mat-7-mot-dieu-uoc-2024-full-hd-lau-tieng-viet
https://www.ticketmelon.com/phim/dem-thanh-doi-san-quy-full-hd-vietsub-mien-phi
https://www.ticketmelon.com/phim/lat-mat-8-vong-tay-nang-2025-full-hd-vietsub-mien-phi
https://www.ticketmelon.com/phim/tham-tu-kien-ky-an-khong-dau-2025-full-hd-vietsub-mien-phi
https://www.ticketmelon.com/phim/thunderbolts-biet-doi-sam-set-2025-full-hd-vietsub-mien-phi
https://cccv.to/latmat7fullvietsub
https://cccv.to/latmat7motdieuuocfullvietnam
https://www.twosapp.com/681a286ba54d4b1a3b151125
https://raindrop.io/icikiwir/babngus-fxfxfxfrsrsrs-55047314
https://wikizilla.org/wiki/User:Bet735nanonano
https://forum.issabel.org/u/Bet735nanonano
https://bandori.party/user/286141/Bet735nanonano/
https://schoolido.lu/user/Bet735nanonano/
https://cinderella.pro/user/203529/Bet735nanonano/
https://nexusstem.co.uk/community/main-forum/bet735nanonano/
https://conecta.club/topic/1307-bet735nanonanocung/
https://www.tipga.com/e/681a31403286fe28bcf14a23
https://yodayo.com/posts/285778fb-07e3-40e2-b144-3f024f3be05c