Frequency of ANCA Positivity in Different Conditions

ANCA-Associated Vasculitis

 • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5% ANCA negative

 • MPA - PR3-ANCA 30%, MPO-ANCA 60%, 10% ANCA negative

 • EGPA - PR3-ANCA 5%, MPO-ANCA 45%, 50% ANCA negative

 • Renal-limited vasculitis - PR3-ANCA 10%, MPO-ANCA 80%, 10% ANCA negative

 • Drug-induced vasculitis - PR3-ANCA 10%, MPO-ANCA 90%, Often high titer, dual positivity for MPO and PR3



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