McDonald Criteria for Diagnosis of Multiple Sclerosis
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Description

McDonald Criteria for Diagnosis of Multiple Sclerosis

 • 2 or more attacks, 2 or more lesions - None. Clinical evidence alone will suffice

 • 2 or more attacks, 1 lesion - Dissemination in space on MR (or await further clinical attack implicating a different CNS site)

 • 1 attack, 2 lesions - Dissemination in time on MR (or await further clinical attack implicating a different CNS site)

 • 1 attack, 1 lesion - Dissemination in space and time (or await further clinical attack implicating a different CNS site)

 • 0 attack progression from onset - One year of disease progression (retrospective or prospective) AND at least 2 out of 3 criteria:

    - Dissemination in space in the brain

    - Dissemination in space in the spinal cord based on 2 or more T2 lesions

    - Positive CSF



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Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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