Amyloidosis - Workup and Diagnostic Algorithm

 • Serum Immunofixation and Serum Free Light Chains

 • Biopsy Surrogate Site (skin, fat pad, bone marrow)

 • Congo Red 

Diagnostic tests after AL amyloidosis diagnosis

 • Serum free light chain ratio

 • Bone marrow biopsy

 • Echocardiogram

 • Serum and urine IFE and 24-h urine electrophoresis

 • Confirm type of amyloid (i .e. mass spectrometry)

 • CBC, CMP, alkaline phosphatase, calcium

 • TnT, proBNP



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