Possible Algorithm for Workup of Fever of Unknown Origin ...

Possible Algorithm for Workup of Fever of Unknown Origin (FUO)

Tier 1 Workup:

 • CBC, comprehensive metabolic panel

 • Blood & urine cultures

 • UA

 • Chest X-ray

 • Abdominal imaging

Tier 2 Workup:

 • Repeat blood cultures

 • HIV, interferon-y release assay (e.g. QuantiFERON)

 • LDH, SPEP, ANA, anti-CCP Ab, ferritin, heterophile antibodies

 • +/- ESR, +/- CRP

 • CT chest

 • Consider: CK, ANCA, cryoglobulin, serum ACE

 • Consider serologies for Coxiella burnetii (Qfever), Bartonella spp and Brucella spp

 • Additional tests for infection depending upon geography/travel

Tier 3 Workup:

 • ? Biopsy - Temporal artery (in elderly pts), Bone marrow, Lymph node, Liver

 • PET scan

 • Tagged WBC scan

 • Lumbar puncture

 • Neuroimaging

 • Echocardiogram

- Dr. Eric Strong @DrEricStrong

#FUO #Algorithm #Fever #Unknown #Origin #Workup #diagnosis
Contributed by

Dr. Gerald Diaz
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
Medical jobs
view all


Related content