Summary of Coagulation Deficiencies

Inherited:

 • Hemophilia A - Deficiency of Factor VIII

 • Hemophilia B -  Deficiency of Factor IX

Acquired:

 • Vitamin K Deficiency - Severe malnutrition, Antibiotics, Malabsorption (e.g. celiac disease, CF, IBD)

 • Anticoagulant Medications - Heparin, LMWH, warfarin, DOACs (e.g. direct factor Xa inhibitors, direct thrombin inhibitors)

 • Advanced Liver Disease - Alcohol, Viral hepatitis, Autoimmune

 • Factor Inhibitors (VIII is most common) - Malignancy, Autoimmune disorders (e.g. RA, SLE), Post-partum

 • Acute DIC - Septic shock, Obstetric catastrophes, Acute promyelocytic leukemia



- Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedicalLectures/



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