Nonossifying Fibroma with Pathologic Fracture - MSK ...

Nonossifying Fibroma with Pathologic Fracture - MSK Radiology
Imaging Findings:
 • Cortically based, geographic, lucent lesion with a sclerotic peripheral margin measured > 3cm.
 • MRI demonstrates the cortically based lesion with T1- and T2-heterogenous signal with regions of hypointense signal representing fibrous/hemosiderin portions. The arrows delineate a nondisplaced linear fracture emanating from the lesion into the femoral metadiaphysis with surrounding marrow edema.
Case description:
 • Nonossifying Fibroma and Fibrous Cortical Defects are histologically similar and sometimes differentiated based on size (NOF > 3cm). Both coined "Fibroxanthoma".
 • Do Not Touch lesions with no follow-up or biopsy necessary in almost all cases. Diagnose with X-RAY; usually resolve by age 20-25.
 • This case shows potential of pathologic fracture in athletes.
 • Multiple NOF's in NF-1 or Jaffe-Campanacci syndrome.
Differential diagnosis for similar lesion:
 • Simple bone cyst: Central, "cyst-like" lesion on MRI without hypointense fibrous tissue.
 • Aneurysmal bone cyst: Eccentric expansile lesion, MRI shows fluid-fluid levels.

Dr. Donald von Borstel @DrvonBorstel

#Nonossifying #Fibroma #NOF #Fracture #clinical #mri #clinical #Radiology #diagnosis #msk 
Contributed by

Dr. Gerald Diaz
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: | Twitter:
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