TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: ...
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Description

TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical illness, high plasma volume transfusion, female of high parity blood donor
 • Pathophysiology: 2 hit mechanism of neutrophil sequestration and activation
 • Timing: Within 6 hours of transfusion
 • Criteria: ARDS Berlin Criteria met without other cause of ARDS to explain symptoms
 • Fever and hypotension?: 33%
 • Treatment: Supportive
TACO:
 • Epidemiology: 0.3-8% of transfused patients
 • Risk factors: Age>60, CKD, CHF, high rate and/or volume of transfusion
 • Pathophysiology: Volume overload
 • Timing: Within 6 hours of transfusion
 • Criteria - At least 3 of (Acute resp distress, elevated BNP, high CVP, left heart failure, positive fluid balance, and CXR with pulmonary edema)
 • Fever and hypotension?: No
 • Treatment: Supportive + diuresis

SCVMC Internal Medicine @SCVMCMed

#TRALI #TACO #Transfusion #Reactions #hematology #diagnosis #comparison #table
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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