Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes), Sideroblastic anemia (sometimes)
Macrocytic RBC: Vitamin B12 or Folate deficiency, Liver Disease, MDS, Chemotherapy (e.g. methotrexate)
Spurr Cell RBC (Acanthocyte): Abetalipoproteinemia, Liver disease, McLeod blood group phenotype, Post-splenectomy, Etc.
Burr Cell RBC (Echinocyte): Artifact, Uremia, Liver disease, Etc.
Schistocyte: Microangiopathic Hemolytic Anemia, Mechanical valve induced, Etc.
Bite Cell RBC: G6PD deficiency, Unstable hemoglobin disorders, Oxidative drugs
Elliptocyte: Hereditary elliptocytosis, Severe iron deficiency anemia
Spherocyte: Hereditary spherocytosis, Autoimmune hemolytic anemia
Stomatocyte: Hereditary stomatocytosis, Liver disease
Target Cell RBC: Thalassemia, Hemoglobinopathies, Post-splenectomy, Liver disease, Artifact
Sickle Cell RBC: Hemoglobin SS disease, Hemoglobin SC disease, Hemoglobin SD disease, S-beta thalassemia
Teardrop: Myelofibrosis, Underlying marrow process/infiltrate, Etc.
Hemoglobin C Crystals: Hemoglobin C disease, Hemoglobin SC disease
Red Cell Agglutinate: Cold autoimmune hemolytic anemia, Paroxysmal cold hemoglobinuria, IgM associated lymphoma, Multiple myeloma
Rouleaux: Chronic liver disease, Malignant lymphoma, Multiple myeloma, Chronic Inflammatory Diseases

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