Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase ...
65
Description

Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary hypertension, Digital ulcers, Primary Biliary Cirrhosis
Anti-RNA polymerase III: Diffuse, Renal crisis, Rapid progressive skin fibrosis
Anti-PM-Sc1: Overlap myositis, Young age of onset
Anti-U3RNP (fibrillarin): African Americans and males, Overlap

BCM IM Residency @BCM_InternalMed

#Systemic #Sclerosis #Autoantibodies #diagnosis #rheumatology
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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