Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary ...
227
Description

Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
    • Etoposide
    • Cyclosporine (sometimes omitted)
    • +/- intrathecal methotrexate (depending on CNS involvement)
 - Followed by hematopoietic cell transplantation
Secondary HLH:
 • Approach varies depending on trigger
 • Almost all patients receive steroids
 • In mild cases associated with infection or autoimmune disease, treatment of underlying condition may spare patient more toxic therapy
 • Options for severe cases include: HLH-94, anakinra, IVIg, rituximab, alemtuzumab, tacrolimus
 • Hematopoietic cell transplantation for refractory disease

- Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedicalLectures/

#HLH #Hemophagocytic #Lymphohistiocytosis #HLH #Treatment #management #hematology
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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