How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is the Patient Receiving Anticoagulants (Vitamin K Antagonists, Heparin, or Direct Thrombin Inhibitor)
Step 3: Is a Systemic Disease Prolonging the PT or APTT?
Step 4: Mixing Studies to identify the cause of Prolonged APTT

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