Eosinophilia - Differential Diagnosis Algorithm
Idiopathic ...

Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS w/ eosinophilia
 • Familial/Genetic: Hyper-lgE (Job) syndrome, familial eosinophilia
Secondary Eosinophilia:
 • Neoplastic: Solid tumors (esp. GI, lung, skin), Heme malig (AML, CML, T-cell leuk/lymphoma, B-cell lymphomas), Systemic mastocytosis, Langerhans cell histiocytosis
 • Allergic: Asthma, Eczema, Drug Hypersensitivity (DRESS, drug-induced eosinophilia, ABPA), Gleich syndrome (episodic angioedema w/ eosinophilia)
 • Infectious: Loeffler syndrome, Helminths (Strongy, Schisto, hookworm, filariasis, trichinella, ascariasis), Scabies, Fungi (Cocci, Aspergillus), Viral (HIV, HTLV-1), Mycobacteria (TB, Leprosy), Bacterial (syphilis, bartonella)
 • Rheum/AI: EGPA, IgG-4 disease, Behcet disease, Sarcoidosis, SLE, Eosinophilic esophagitis, Eosinophilic pneumonia, Adrenal insufficiency, Chronic inflammatory disease: e.g. IBD

Stanford Internal Medicine Chiefs @StanfordChiefs

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Contributed by

Dr. Gerald Diaz
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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