Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm



1. Definition: T.bili elevation + >20% conjugated

2. Obtain RUQ US to look for ductal dilation

3. No dilation = intrahepatic cholestasis - rule out non-ICU vs ICU causes

4. MRCP, ERCP, liver biopsy



Matthew Ho, MD PhD @MatthewHoMD



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