ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis



MPA → usually p-ANCA

GPA → usually c-ANCA

EGPA → ANCA in 40-50%



P-ANCA (MPO)

C-ANCA (PR3)

X-ANCA (elastase, cathepsin, lysozyme, others) - Perinuclear pattern



Drug-Induced ANCA Vasculitis

Levamisole-Induced ANCA Vasculitis

Hydralazine-Induced ANCA Vasculitis



By Andrew Sanchez M.D. @ASanchez_PS



#ANCA #Vasculitis #AAV #Differential #Diagnosis #laboratory