Invasive Candidiasis (IC)



Diagnosis:

Culture:

 • Gold standard, but Slow (~2-3 days), 50% sensitivity

 • Blood Sample

 • Sterile-site biopsy

Non-culture-based tests:

 • Beta-D-Glucan

 • Molecular Tests

Conduct antifungal susceptibility testing (AFST) to guide therapy



First Line Targeted Treatment (with AFST)

 • Echinocandin (strong recommendation)

 • Lipid amphotericin B

 • Fluconazole (intravenous or oral) 



Additional management:

 • Dilated Funduscopic Exam

 • CVC Removal

 • Infectious Diseases Consults

 • Echocardiogram



#Invasive #Candidiasis #IC #antifungal #diagnosis #management #candida #auris #treatment