Bacteremia Quick Reference - Treatment Duration



Gram Negative Bacteremia:

 • Avoid: Aminoglycosides and tigecycline

 • Catheters should be removed in septic shock, suppurative thrombophlebitis, IE, infection due to P. aeruginosa

 • ESBL: carbapenems the drug class of choice, some strains be susceptible may to cefepime

 • Duration: 7 days preferred, initially IV, consider switching to oral if good bioavailability

 • No follow up cultures required



Gram Positive Bacteremia:

 • S. aureus and S. lugdunensis - 14 days of IV therapy if meets all of the following criteria:

    - Absence of IE

    - No indwelling devices

    - Follow-up blood cultures are negative.

    - No fever within 48 -72 hours after initiating therapy

    - No evidence of metastatic infection.

 • Streptococcus Pneumoniae 10-14 days therapy. Consider switching to oral if good bioavailability

 • Enterococcus 5-7 days therapy (if repeated blood cultures drawn at 24 hours are negative) Use DENOVA score

 • Group C and Group G strep - 14 days therapy



By @TheIDtrivia



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