Syphilis Staging - Primary, Secondary, Latent and Tertiary - Timing and Features


Primary syphilis classically presents with a chancre at the inoculation site. 
Secondary syphilis is classically characterized by condylomata lata which are papules at mucocutaneous junctions.

phase.


The latent stage is dichotomized into early and late stages. Early latent stage occurs less than one year after primary infection and late latent stage occurs greater than one year after primary infection. 
Tertiary syphilis is due to an obliterative endarteritis that can affect any organ system but is divided into three subtypes: benign, cardiovascular, and central nervous system.
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