Primary and Secondary Causes of Osteoporosis

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Primary and Secondary Causes of Osteoporosis


Primary osteoporosis 
 - idiopathic juvenile osteoporosis 
 -  postmenopausal osteoporosis 
 - senile osteoporosis 

Secondary osteoporosis 
Endocrine origin 
 - hypogonadism 
 - hypercortisolism (steroid medication. Cushing syndrome) 
 - hyperthyroidism 
 - hyperparathyroidism 
 - hyperprolactinemia 
 - diabetes mellitus 
Gastrointestinal diseases 
 - chronic inflammatory bowel diseases 
 - malabsorption 
 - malnutrition 
 - primary biliary cirrhosis 
 - lactose intolerance 

Bone marrow diseases 
 - multiple myeloma (plasmacytoma) 
 - diffuse bone metastases 

Rheumatological and connective tissue diseases 
 - rheumatoid arthritis 
 - osteogenesis imperfecta 
 - Ehlers-Danlos syndrome 
 - Marfan syndrome 
 - homocystinuria 

Other causes 
 - immobilization 
 - chronic alcoholism 
 - organ transplantation 
 - other 


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