Hepatosplenic T-cell lymphoma involving hepatic sinusoids.


HSTL also involves BM sinusoids and splenic red pulp cords and sinuses in essentially all cases.


Usually young males, TCR g/d+, CD4-, CD8-/+, TIA1+


Isochromosome 7q is present in most cases.


Median survival <2 years.


 - Kyle Bradley, MD

@KyleBradleyMD


#Hepatosplenic #TCell #Lymphoma #HSTCL #Pathology #Microscopy #Oncology #Clinical