Eosinophilic angiocentric fibrosis: IgG4-related disease of the upper aerodigestive tract. Distinctive concentric (onion-skin) perivascular fibrosis and mixed inflammation with prominent eosinophils. Usually >50 IgG4+ plasma cells/HPF, IgG4:IgG >40%.


- Dr. Lisa Rooper @LisaRooperMD 


#Eosinophilic #angiocentric #fibrosis #Pathology #Clinical #Microscopy