Oral anti-hypertensives with relative fast onset of action (Hypertensive Emergency)



The key concern with oral antihypertensive agents is how rapidly they take effect.  As in any other situation where you're up-titrating medications (e.g. procedural sedation), it's important to allow one dose of medication to take effect before you escalate the dose.



The ideal oral antihypertensive will take effect in under ~2 hours.  This allows for a fairly prompt up-titration of oral doses, which allows rapid weaning of the IV antihypertensive agent.



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