Enterocytes release absorbed lipids the form of triglyceride-rich chylomicrons. These are acted upon by endothelial cells producing fatty acids, which are stored in tissues. The remnants of chylomicrons are transported to liver cells where they are a source of dietary cholesterol. The liver uses this and hepatically
produced cholesterol to synthesize very-low-density lipoproteins (VLDLs) and bile acids. VLDLs are released into the blood and supply tissues with fatty acids. The low density liproprotein (LDL) remnants either return to the liver or supply cells with cholesterol.
#Lipoprotein #Cholesterol #Metabolism #Pathophysiology