Impact and Challenges With Vitamin D to Treat Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease 



Ergocalciferol (D2)

Cholecalciferol (D3)

 - Effective in repleting 25-D and 1,25-D in patients with early-stage CKD and adequate kidney function 

ER Calcifediol 

 - Effective in repleting 25-D and 1,25-D in patients with CKD 3 and 4 

 - Effectively suppresses SHPT 

Calcitriol 

 - Biologically active VDR agonist 

 - Effectively suppresses SHPT 

 - Reduces abnormal high bone turnover 

Doxercalciferol 

 - Suppresses SHPT similar to or better than calcitriol 

 - Noted reduction in serum bone-specific alkaline phosphatase and osteocalcin 

Alphacalcidol 

 - Suppresses SHPT similar to or better than calcitriol 

Paricalcitol 

 - Biologically active VDR agonist 

 - Effectively suppresses SHPT 

 - Noted reduction in serum bone-specific alkaline phosphatase and osteocalcin 



Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ



#VitaminD #Secondary #Hyperparathyroidism #CKD #Nephrology #Management #Pharmacology #Cholecalciferol #Calcitriol