Biologic therapy for eosinophilic asthma 
• Mepolizumab ...
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Description

Biologic therapy for eosinophilic asthma 

• Mepolizumab (Nucala) 

  • Anti-lL-5, 100 mg SQ q4 weeks 

  • Peripheral eosinophils >150/microL, need VZV vaccine 

• Reslizumab (Cinqair) 

  • Anti-lL-5, 3 mg/kg IV q4 weeks 

  • Peripheral eosinophils >400/microL 

• Benralizumab (Fasenra) 

  • Anti-lL-5 receptor, 30 mg SQ q4 weeks x3 doses -> q8 weeks 

  • Peripheral eosinophils >300/microL 

• Dupilumab (Dupixent) 

  • Anti-lL-4/13 receptors, 600 mg SQ x 1 -> 300 mg q2 weeks 

  • Peripheral eosinophils >150/microL 



Dr. Avraham Z. Cooper, MD @AvrahamCooperMD



#eosinophilic #asthma #Biologic #therapy #Medications #pharmacology #pulmonary #management 
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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