Scleroderma Renal Crisis - Diagnosis and management



Diaqnosis

 • De novo arterial hypertension of normotensive form +++

 • Proteinuria > 2+

 • Hematuria > 2+

 • Thrombocytopenia < 100 G/L

 • Hemolysis

 • Increased serum creatinine >50% 

 • Signs of thrombotic microangiopathy

Therapeutic manaqement

 • Angiotensin-converting enzyme inhibitors +++

 • If needed to control blood pressure: IV nicardipin/urapidil

 • Avoid diuretics and ß-blockers

 • Discuss dialysis with nephrologist

 • Renal transplantation : to discuss after 2 years of dialysis (possible late recovery)



By Dr.Pauline Martins @PaulineM8140 via Dr. Benjamin Terrier @TerrierBen



#Scleroderma #RenalCrisis #Diagnosis #management #nephrology