Low-dose aspirin and low-molecular-weight heparin in ...
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Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy



• No previous history of thrombosis or pregnancy complications BUT high-risk aPL profile:

  Aspirin (75-100 mg/day)

• Previous history thrombotic APS (arterial or venous): consensus +++

  Aspirin (75-100 mg/day) + curative low-molecular-weight heparin (LMWH)

• Previous history of obstetric APS: EULAR Recommendations 2019

  - History of 23 recurrent spontaneous miscarriages weeks of gestation OR fetal loss > 10 weeks of gestation : Aspirin + preventive LMWH, continued for 6 weeks after delivery

  - History of delivery <34 weeks of gestation (eclampsia, preeclampsia or placental insufficiency): Aspirin ± preventive LMWH, continued for 6 weeks after delivery

  - History of "non-criteria" obstetric APS: Aspirin ± preventive LMWH, continued for 6 weeks

after delivery



By Dr. Chloé Baillou @BaillouChloe via Dr. Benjamin Terrier @TerrierBen

 

#Antiphospholipid #Syndrome #APS #pregnancy #Obstetrics #Anticoagulation #Aspirin #LWMH #Dosing #Pharmacology
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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