ID Approach to Fever and Rash - Diagnostic Algorithm

Central Maculopapular (most common):

Measles, Parvovirus 819 / EBV, Acute HIV, WNV, Mycoplasma, Leptospirosis, Viral/Drug Exanthemas

Peripheral Maculopapular:

RMSF, Coxsackievirus A16 (HFMD), Parvovirus B19 (PPGSS), Secondary syphilis, EM (HSV, Mycoplasma), Infective endocarditis, Drug eruption

Confluent Desquamative:

Scarlet fever, TSS (Strep/Staph), SJS/TEN, DRESS, AGEP, Kawasaki, Erythroderma (psoriasis, drugs, lymphoma)

Vesiculobullous or Pustular:

SJS/TEN, HSV/VZV, Coxsackievirus A16 (HFMD), Pyoderma gangrenosum, Rickettsialpox, Disseminated gonococcal, Vibrio vulnificus, AGEP, Pustular Psoriasis

Purpuric:

RMSF, Neisseria meningitidis, Purpura fulminans, Viral hemorrhagic fevers, Parvovirus B19 (PPGSS), Vasculitis

Nodular:

Disseminated fungal, EN (drugs, Strep, mycobacterial, Yersinia), Bacillary angiomatosis, Sweet syndrome

Eschar:

Ecthyma (Pseudomonas, mold), Plague, anthrax, tularemia, Rickettsia akari (Rickettsialpox), Rickettsia conorii (Boutonneuse), Rickettsia africae (ATBF), Orientia tsutsugamushi (scrub), Spider bite



- WuidQ: Washington University ID Questions @WuidQ



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