APRV - Overview 



Airway pressure release ventilation (APRV) uses prolonged periods of high continuous positive airway pressures interrupted by brief episodes of pressure release to a lower pressure 

 • Intended as a rescue therapy for severe ARDS (low lung compliance with high oxygenation requirements)



Advantages: Alveolar recruitment and improved oxygenation, preservation of spontaneous breathing, lower sedation requirements

Disadvantages: Risk of volutrauma, increased work of breathing and energy expenditure, consistently increased intrathoracic pressures may adversely affect hemodynamics



M. Daniyal Hashmi, MD @MDaniyalHashmi1



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